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The human airway basal cell signature was also enriched for at the very least 35 genes encoding different ion transporters including potassium channels and solute carrier proteins (Desk 8)

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Among extracellular matrix factors, 5 laminin subunits corresponding to the a, b1, b3, c1...
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Hmox1 catalyzes the rate-limiting phase in heme degradation and is included in shielding cells in opposition to several pathological insults which includes ischemic accidents and peroxide toxicity [93,94]

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Interestingly, ATF3 is also believed to be an important player in the integral tension...
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This is regular with the desired cleavage internet site of quinolones, which induce DNA cleavage at and all around G/C abundant sequences [40] and in contrast with the topoisomerase II-mediated DNA DSB induced by doxorubicin, which favors a 39A at the website of cleavage [forty one]

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Principal scaffold-relevant cytotoxic activities of these medicines arise from induction of reactive oxygen species...
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Channel activity was analyzed as NPo = I/i, wherever I is mean complete recent in a patch and i is unitary current at this voltage

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Therefore, our outcomes supply evidence for the speculation that ENaC regulation by modest G...