Product Name: Phospho-CHEK1-S345 Polyclonal Antibody
Host Species: Rabbit
Purity: Affinity purificationMedchemexpress.com
Isotype: IgG
Background: The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR,
Immunogen: A phospho specific peptide corresponding to residues surrounding S345 of human CHEK1
CAS NO:405554-55-4 Product: SB-590885
Swiss Prot: O14757
Synonyms: CHK1
Calculated MW: 54kDa
Observed MW: Refer to figuresRIP kinase inhibitors
Reactivity: Human
Test Dapplications: WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Postivie Samples: HT-29 treated with UV,HepG2 treated with UV
Celluar Location: Nucleus,Cytoplasm,cytoskeleton,microtubule organizing center,centrosomePubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19056895?dopt=Abstract
