Product Name: Phospho-PAK1-T423/PAK2-T402/PAK3-T421 Polyclonal Antibody
Host Species: Rabbit
Purity: Affinity purificationMedchemexpress
Isotype: IgG
Background: The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complex
Immunogen: A phospho specific peptide corresponding to residues surrounding T423 of human PAK1
CAS NO:53185-12-9 Product: Fagomine
Swiss Prot: Q13153;Q13177;O75914
Synonyms: p21-activated kinase 1;PAK-1;p65-PAK;Alpha-PAK;
Calculated MW:
Observed MW: Refer to FiguresPI4K inhibitors
Reactivity: Human Mouse Rat
Test Dapplications: IHC IF
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Postivie Samples:
Celluar Location: Cytoplasm,Cell junction,focal adhesion,Cell membrane,Cell projection,ruffle membrane,invadopodium,Nucleus,perinuclear region,Membrane,Lipid-anchorPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19696014?dopt=Abstract
