N chromosomes vary widely in a species and biogenesis of miRNA
N chromosomes vary widely in a species and biogenesis of miRNA largely depends on transcription or post-transcriptional processing of coding genes. Front Genet. 2014;5:100. 12. Su WL, Kleinhanz RR, Schadt EE. Characterizing the role of miRNAs within gene regulatory networks using integrative genomics techniques. Mol Syst Biol. 2011;7:490. 13. Zhou Y, Wang J, Lu X, Song X, Ye Y, Zhou J, et al. Evaluation of six SNPs of MicroRNA machinery genes and risk of schizophrenia. J Mol Neurosci. 2013;49(3):594?. 14. Yi R, Pasolli HA, Landthaler M, Hafner M, Ojo T, Sheridan R, et al. DGCR8dependent microRNA biogenesis is essential for skin development. Proc Natl Acad Sci U S A. 2009;106(2):498?02.Gupta et al. BMC Genomics (2016) 17:Page 14 of15. Schneider MR. MicroRNAs as novel players in skin development, homeostasis and disease. Br J Dermatol. 2012;166(1):22?. 16. Bonazzi VF, Stark MS, Hayward NK. MicroRNA regulation of melanoma progression. Melanoma Res. 2012;22(2):101?3. 17. Ballabio E, Mitchell T, van Kester MS, Taylor S, Dunlop HM, Chi J, et al. MicroRNA expression in Sezary syndrome: identification, function, and diagnostic potential. Blood. 2010;116(7):1105?3. 18. Joyce CE, Zhou X, Xia J, Ryan C, Thrash B, Menter A, et al. Deep sequencing of small RNAs from human skin reveals major PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/28388412 alterations in the psoriasis miRNAome. Hum Mol Genet. 2011;20(20):4025?0. 19. Sonkoly E, Janson P, Majuri ML, Savinko PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/28914615 T, Fyhrquist N, Eidsmo L, et al. MiR-155 is overexpressed in patients with atopic dermatitis and modulates T-cell proliferative responses by targeting cytotoxic T lymphocyte-associated antigen 4. J Allergy Clin Immunol. 2010;126(3):581?. e581-520. 20. Li Q, Stram A, Chen C, Kar S, Gayther S, Pharoah P, et al. Expression QTL-based analyses reveal candidate causal genes and loci across five tumor types. Hum Mol Genet. 2014;23(19):5294?02. 21. Ludwig RJ, Muller S, Marques A, Recke A, Schmidt E, Zillikens D, et al. Identification of quantitative trait loci in experimental epidermolysis bullosa acquisita. J Invest Dermatol. 2012;132(5):1409?5. 22. Alberts R, Terpstra P, Li Y, Breitling R, Nap JP, Jansen RC. Sequence polymorphisms cause many false cis eQTLs. PLoS One. 2007;2(7):e622. 23. Keane TM, Goodstadt L, Danecek P, White MA, Wong K, Yalcin B, et al. Mouse genomic variation and its effect on phenotypes and gene regulation. Nature. 2011;477(7364):289?4. 24. Winter J, Jung S, Keller S, Gregory RI, Diederichs S. Many roads to maturity: microRNA biogenesis pathways and their regulation. Nat Cell Biol. 2009;11(3):228?4. 25. Jankowsky A, Guenther UP, Jankowsky E. The RNA helicase database. Nucleic Acids Res. 2011;39(Database issue):D338?41. 26. Li Y, Liu H, Lai C, Du X, Su Z, Gao S. The Lin28/let-7a/c-Myc pathway plays a role in non-muscle invasive bladder cancer. Cell Tissue Res. 2013;354(2):533?1. 27. Kramer A, Green J, Pollard Jr J, Tugendreich S. Causal analysis U0126-EtOH msds approaches in Ingenuity Pathway Analysis. Bioinformatics. 2014;30(4):523?0. 28. Baumjohann D, Ansel KM. MicroRNA-mediated regulation of T helper cell differentiation and plasticity. Nat Rev Immunol. 2013;13(9):666?8. 29. Liu H, Kohane IS. Tissue and process specific microRNA-mRNA co-expression in mammalian development and malignancy. PLoS One. 2009;4(5):e5436. 30. Schmidt MF. Drug target miRNAs: chances and challenges. Trends Biotechnol. 2014. 31. De Guire V, Robitaille R, Tetreault N, Guerin R, Menard C, Bambace N, et al. Circulating miRNAs as sensitive and specific biomarkers for the diagno.
