Ontrol group was 17.2 , which was not various from the case group (18.6 ) (P 0.05). History of antibiotic consumption was significantly larger in the VAP individuals (CaseControl = 429).4.1. Threat Factors Pneumonia4. ResultsAmong 675 patients, 150 instances of VAP were documented within the study period, representing a probable VAP incidence of 22 (per ventilated patient 48 hoursICUVariables Cases (n = 150) 36.55 (14.47) 14.07 (11.33) 112 (74.7) 43 (28.7) 26 (17.three) 51 (34) 81 (54) 42 (28) 17.70 (3.81)Table 1. Traits of the Study Population (Case and Manage) and Crude Odds Ratio Age, mean (SD) Control (n = 150) 31.40 (13.77) 13.16 (5.13) three.24 (1.59) 91 (60.7) 9 (6)The characteristics of the study population (case and handle) and crude odds ratio are shown in We We discovered considerable threat related with age, APACHE I, length of hospital keep, previous antibiotic use and form of poisoning in the univariate evaluation. As shown in Table 2, applying the multivariate analysis for the risk aspects, revealed that APACHE II, length of hospital remain and form of poisoning were important predictors of pneumonia with odds ratios ranging from 1.28 to three.74.forVentilator-AssociatedCrude OR two.95 0.21 1.15 1 1 1.23 1.02 1.APACHE II, mean (SD)Length of hospital stay, mean (SD) Gender (male), No. ( ) 11 – 15 3-5 Preceding antibiotics, No. ( ) Glasgow coma score, No. ( ) six – ten Type of poisoning, No. ( ) Othersa Opioida CNS depressantsa46 (30.7) 85 (56.7) 19 (12.7)0.04 – 0.26 0.69 – 1.92 NA NA2.23 – 3.89 0.93 – 1.1.01 – 1.04 1.19 – 1.CI (95 ) 0.0001 0.0001 0.0001 0.0001 0.560 NA NA 0.P ValueTable two. Threat Elements for the Improvement of Ventilator-Associated Pneumonia in Poisoned Patients (Multivariate Logistic Regression)a Variables APACHE II Opioid Other folks Odds Ratio 1.28 two.15 1 95 Self-confidence Interval 1.27 – three.37 1.16 – six.02 0.15 – two.11 NA 1.11 – 1.46 0.0001 0.0001 0.027 NA P ValueAbbreviation: NA, not offered. aPesticide, Methanol, 3, 4-Methylenedioxy-Methamphetamine (MDMA) and multi drugs; Opium, heroin and methadone; Antidepressant, Benzodiazepine and anti-convulsive.74 (49.3)25 (16.7)65 (43.4) 44 (29.three) 41 (27.3)1.92 2.23 3.0.92 – four.05 1.74 – five.99 2.41 – 7.0.084 0.0001 0.Length of hospital keep Type of poisoning CNS depressantsIran Red Crescent Med J. 2016;18(1):eAbbreviation: NA, not available. aThe model was adjusted with age and gender.0.three.0.Hashemian M et al.4.2. Microbiological ResultsMicrobiological evaluation benefits in the respiratory sample (tracheobronchial aspirate) within the VAP group are shown in Table three. All round, probably the most frequent pathogens causing pneumonia had been Methicillin-resistant Staphylococcus ATP-polyamine-biotin web aureus (56.7 ) and Acinetobacter spp. (12.7 ). In those that had died, MRSA (39.29 ), Acinetobacter sp. (21.43 ) and Pseudomonas aeruginosa (21.43 ) were one of the most frequent pathogens while in the survivors, MRSA accounted for 60.six from the pathogens followed by Klebsiella PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21384849 and Acinetobacter spp. There was no association among the pathogens and previously utilized antibiotics (P = 0.9). Blood culture was good in 18 (14.eight ) and 4 (14.three ) sur-vivors and non-survivors, respectively (P = 0.9). Moreover, MRSA was constructive in 95.five of blood cultures in VAP cases. Urine culture was optimistic in 13 (10.7 ) and five (17.9 ) survivors and non-survivors, respectively (P = 0.two).4.3. Predictors of Intensive Care Unit Mortality Amongst Patients With Ventilator Linked PneumoniaTable 3. Microbiological Identification in 150 Individuals With Ventilator-Ass.
