Name :
Anti-BAP1 Rabbit antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
BAP1 Rabbit monoclonal antibody
Tested applications :
WB, FC
Species reactivity :
Human
Alternative names :
Immunogen :
Isotype :
IgG
Preparation :
Antigen: Recombinant protein of human BAP1
Clonality :
Monoclonal
Formulation :
50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA
Storage instructions :
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Applications :
WB: 1/1000FC: 1/20
Background :
This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013]
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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