Name :
GRIN1 Polyclonal Antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Polyclonal antibody to GRIN1
Tested applications :
IHC, IF
Species reactivity :
Human, Rat
Alternative names :
GRIN1 antibody; GluN1 antibody; MRD8 antibody; NMD-R1 antibody; NMDA1 antibody; NMDAR1 antibody; NR1 antibody; glutamate receptor ionotropic, NMDA 1 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Antigen: A synthetic peptide of human GRIN1
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage instructions :
Store at -20℃. Avoid freeze / thaw cycles.
Applications :
IHC 1:50 – 1:200IF 1:50 – 1:200
Background :
Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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