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Name :
GUCY2C Polyclonal Antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
Polyclonal antibody to GUCY2C

Tested applications :
WB

Species reactivity :
Human, Mouse

Alternative names :
GUCY2C antibody; DIAR6 antibody; GC-C antibody; GUC2C antibody; MECIL antibody; MUCIL antibody; STAR antibody; guanylate cyclase 2C antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-330 of human GUCY2C (NP_004954.2).

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage instructions :
Store at -20℃. Avoid freeze / thaw cycles.

Applications :
WB 1:500 – 1:2000

Background :
Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptides guanylin and uroguanylin.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel