Name :
HADHA antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HADHA Mouse Monoclonal antibody. Positive WB detected in A375 cells, HepG2 cells, Jurkat cells. Positive IHC detected in human heart tissue, human liver tissue. Positive IF detected in HepG2 cells. Observed molecular weight by Western-blot: 79 kDa
Tested applications :
ELISA, WB, IHC, IF
Species reactivity :
Human,Mouse; other species not tested.
Alternative names :
78 kDa gastrin binding protein antibody; ECHA antibody; HADH antibody; HADHA antibody; LCHAD antibody; MTPA antibody; TP ALPHA antibody
Immunogen :
Human HADHA Recombinant protein (GST tag)
Isotype :
Mouse IgG1
Preparation :
This antibody was obtained by immunization of HADHA recombinant protein (Accession Number: NM_000182). Purification method: Protein G purified.
Clonality :
Monoclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200IF: 1:50-1:500
Background :
HADHA(Trifunctional enzyme subunit alpha, mitochondrial) is also named as HADH,78 kDa gastrin-binding protein.It belongs to the enoyl-CoA hydratase/isomerase family in the N-terminal section and the 3-hydroxyacyl-CoA dehydrogenase family in the central section.It harbors the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities.Defects in HADHA are a cause of trifunctional protein deficiency (TFP deficiency) and long-chain 3-hydroxyl-CoA dehydrogenase deficiency (LCHAD deficiency) and maternal acute fatty liver of pregnancy (AFLP).
References :
Du Y, Meng Y, Zhu J. Quantitative proteomic study of myocardial mitochondria in urea transporter B knockout mice. Proteomics. 14(17-18):2072-83. 2014.
Related websites: https://www.medchemexpress.com/antibodies.html
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