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Name :
HDAC1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
HDAC1 Mouse Monoclonal antibody. Positive WB detected in Hela cells, HEK-293 cells, HepG2 cells, Jurkat cells. Observed molecular weight by Western-blot: 65kD

Tested applications :
ELISA, WB

Species reactivity :
Human; other species not tested.

Alternative names :
DKFZp686H12203 antibody; GON 10 antibody; HD1 antibody; HDAC1 antibody; histone deacetylase 1 antibody; RPD3 antibody; RPD3L1 antibody

Immunogen :
Human HDAC1 Recombinant protein (His tag)

Isotype :
Mouse IgG1

Preparation :
This antibody was obtained by immunization of HDAC1 recombinant protein (Accession Number: NM_004964). Purification method: Protein G purified.

Clonality :
Monoclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:1000-1:10000

Background :
Histone deacetylases(HDAC) are a class of enzymes that remove the acetyl groups from the lysine residues leading to the formation of a condensed and transcriptionally silenced chromatin. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex, which is responsible for gene expression silencing. It also plays an important role in the control of cell proliferation and differentiation by interacting with RB, p53 and other transcription factors. At least 4 classes of HDAC were identified. As a class I HDAC, HDAC 1 was primarily found in the nucleus. This antibody is raised against residues near the C terminus of human HDAC1.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel