Name :
HDGFRP3 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HDGFRP3 Rabbit Polyclonal antibody. Positive IF detected in MCF-7 cells. Positive IHC detected in human prostate cancer tissue. Positive WB detected in human brain tissue, Y79 cells. Positive IP detected in mouse testis tissue. Observed molecular weight by Western-blot: 30 kDa
Tested applications :
ELISA, WB, IHC, IF, IP
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
CGI 142 antibody; HDGF 2 antibody; HDGF2 antibody; HDGFRP3 antibody; HRP 3 antibody; HRP-3 antibody
Immunogen :
Human HDGFRP3 Recombinant protein (GST tag)
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of HDGFRP3 recombinant protein (Accession Number: NM_016073). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IP: 1:200-1:1000IHC: 1:20-1:200IF: 1:20-1:200
Background :
HDGFRP3, also named as Hepatoma-derived growth factor-related protein 3 or HDGF2, is a 203 amino acid protein, which contains 1 PWWP domain and belongs to the HDGF family. HDGFRP3 detected in testis, heart, spinal cord and brain. HDGFRP3 as a nuclear potein enhances DNA synthesis and may play a role in cell proliferation.
References :
Yun HS, Hong EH, Lee SJ. Depletion of hepatoma-derived growth factor-related protein-3 induces apoptotic sensitization of radioresistant A549 cells via reactive oxygen species-dependent p53 activation. Biochemical and biophysical research communications. 439(3):333-9. 2013. Yun HS, Baek JH, Yim JH. Knockdown of hepatoma-derived growth factor-related protein-3 induces apoptosis of H1299 cells via ROS-dependent and p53-independent NF-κB activation. Biochemical and biophysical research communications. 449(4):471-6. 2014.
Related websites: https://www.medchemexpress.com/antibodies.html
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