Name :
HEATR2 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HEATR2 Rabbit Polyclonal antibody. Positive WB detected in HEK-293 cells, K-562 cells. Positive IHC detected in human lung tissue, human kidney tissue. Positive IF detected in HEK-293 cells. Observed molecular weight by Western-blot: 93 kDA
Tested applications :
ELISA, WB, IHC, IF
Species reactivity :
Human, Rat; other species not tested.
Alternative names :
FLJ20397 antibody; FLJ25564 antibody; FLJ31671 antibody; FLJ39381 antibody; HEAT repeat containing 2 antibody; HEATR2 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of HEATR2 recombinant protein (Accession Number: NM_017802). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200IF: 1:10-1:100
Background :
HEATR2 also termed as HEAT repeat containing 2 is an 855 amino acid protein. HEATR2 is a member of a family of ten other uncharacterized HEAT-repeat-containing proteins, which contains HEAT (Huntingtin, elongation factor 3 (EF3), protein phosphatase 2A (PP2A) and the yeast PI3-kinase Tor1) repeats. HEAT repeats form rod-like helical structures that are involved in intracellular transport. HEATR2 play an important role in dynein arm transportation or assembly. HEATR2 mutation is implicated in Primary ciliary dyskinesia 18.
References :
Diggle CP, Moore DJ, Mali G. HEATR2 plays a conserved role in assembly of the ciliary motile apparatus. PLoS genetics. 10(9):e1004577. 2014.
Related websites: https://www.medchemexpress.com/antibodies.html
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