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Name :
Anti-BDNF Rabbit antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
BDNF Rabbit polyclonal antibody

Tested applications :
WB, IHC-P, ICC/IF

Species reactivity :
Human, Mouse, Rat

Alternative names :

Immunogen :

Isotype :
Rabbit IgG

Preparation :
Antigen: A synthesized peptide derived from human BDNF

Clonality :
Polyclonal

Formulation :
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage instructions :
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Applications :
WB: 1/1000-1/2000IHC: 1/50-1/200

Background :
Swiss-Prot Acc.P23560.Neurotrophins function to regulate naturally occurring cell death of neurons during development. The prototype neurotrophin is nerve growth factor (NGF), originally discovered in the 1950s as a soluble peptide promoting the survival of, and neurite outgrowth from, sympathetic ganglia. Three additional structurally homologous neurotrophic factors have been identified. These include brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3) and neurotrophin-4 (NT-4) (also designated NT-5). These various neurotrophins stimulate the in vitro survival of distinct, but partially overlapping, populations of neurons.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel