Name :
HECTD3 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HECTD3 Rabbit Polyclonal antibody. Positive WB detected in MCF7 cells. Observed molecular weight by Western-blot: 97kd
Tested applications :
ELISA, WB
Species reactivity :
Human, Mouse; other species not tested.
Alternative names :
FLJ21156 antibody; FLJ31983 antibody; HECT domain containing 3 antibody; HECTD3 antibody; RP11 69J16.1 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of HECTD3 recombinant protein (Accession Number: BC019105). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000
Background :
HECTD3(HECT domain-containing protein 3) may be involved in the regulation of mitotic metaphase/anaphase transition. It can specifically ubiquitinate TRIOBP and target it for proteasomal degradation and it can also mediates the ubiquitination of STX8. HECTD3 is a new oncogenic E3 ligase in human prostate cancer.( Li Y, etc. 2008) HECTD3 may facilitate cell cycle progression via regulating ubiquitination and degradation of Tara(PMID:18194665). It has 2 isoforms produced by alternative splicing.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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