Name :
HGD antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HGD Rabbit Polyclonal antibody. Positive IHC detected in human liver tissue. Positive WB detected in human liver tissue, HeLa cells. Observed molecular weight by Western-blot: 50kd
Tested applications :
ELISA, WB, IHC
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
AKU antibody; FLJ94126 antibody; HGD antibody; HGO antibody; Homogentisate 1 antibody; 2 dioxygenase antibody; Homogentisate oxygenase antibody; Homogentisic acid oxidase antibody; Homogentisicase antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of HGD recombinant protein (Accession Number: BC020792). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200
Background :
Homogentisate1,2-dioxygenase (HGD), also named as HGO, is a mononuclear Fe(II)-dependent oxygenase that catalyzes the third step in the pathway for the catabolism of tyrosine, the conversion of homogentisate (HG) to maleylacetoacetate (MAA) and it can exsit as a dimer or trimer(PMID:14678794). HGD consists of a single type of subunit with no intermolecular disulfide bridges and requires Fe2+ as a cofactor(PMID: 7705358). Defects in HGD are the cause of alkaptonuria (AKU)(PMID:10594001).
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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