Name :
HIGD1A antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HIGD1A Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, HepG2 cells, rat brain tissue, rat kidney tissue. Positive IF detected in HepG2 cells. Positive IHC detected in human testis tissue. Observed molecular weight by Western-blot: 10kd
Tested applications :
ELISA, WB, IHC, IF
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
DKFZp564K247 antibody; HIG1 antibody; HIG1 domain family member 1A antibody; HIGD1A antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of HIGD1A recombinant protein (Accession Number: NM_001099669). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200IF: 1:10-1:100
Background :
HIG1 domain family member 1A (HIGD1A) is a proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. May play a role in the assembly of respiratory supercomplexes (22342701). It is induced by hypoxia induction.This antibody is a rabbit polyclonal antibody raised against a full-length human HIGD1A protein.
References :
Hayashi T, Asano Y, Shintani Y. Higd1a is a positive regulator of cytochrome c oxidase. Proceedings of the National Academy of Sciences of the United States of America. 112(5):1553-8. 2015. Ameri K, Rajah AM, Nguyen V. Nuclear localization of the mitochondrial factor HIGD1A during metabolic stress. PloS one. 8(4):e62758. 2013.
Related websites: https://www.medchemexpress.com/antibodies.html
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