Name :
HSD3B7 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HSD3B7 Rabbit Polyclonal antibody. Positive IHC detected in human pancreas cancer tissue, human kidney tissue, human liver tissue. Positive WB detected in mouse liver tissue. Observed molecular weight by Western-blot: 36 kDa
Tested applications :
ELISA, WB, IHC
Species reactivity :
Human, Mouse; other species not tested.
Alternative names :
3 beta HSD VII antibody; C(27) 3 beta HSD antibody; HSD3B7 antibody; PFIC4 antibody; SDR11E3 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of HSD3B7 recombinant protein (Accession Number: NM_025193). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200
Background :
HSD3B7(3 beta-hydroxysteroid dehydrogenase type 7) is also named as 3-beta-HSD VII,C(27) 3-beta-HSD and belongs to the 3-beta-HSD family. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids and HSD VII is active against four 7-alpha-hydroxylated sterols. This enzyme is expressed predominantly in the liver(PMID:11067870). Defects in HSD3B7 are the cause of congenital bile acid synthesis defect type 1 (CBAS1). It has 2 isoforms produced by alternative splicing.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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