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Name :
HSN2 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
HSN2 Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue, MCF7 cells. Positive IHC detected in human kidney tissue, human gliomas tissue. Observed molecular weight by Western-blot: 65 kDa

Tested applications :
ELISA, WB, IHC

Species reactivity :
Human, Mouse; other species not tested.

Alternative names :
HSAN2 antibody; HSN2 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of HSN2 recombinant protein (Accession Number: BC130469). Purification method: Antigen Affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200

Background :
HSN2, also named as WNK1, KDP, KIAA0344, PRKWNK1, P65 and hWNK1, is a serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. It acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. WNK1 may also play a role in actin cytoskeletal reorganization. This antibody detects the 65 kDa protein (Erythrocyte 65 kDa protein, P65).

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel