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Name :
HSPA13 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
HSPA13 Rabbit Polyclonal antibody. Positive IHC detected in human endometrial cancer tissue. Positive IP detected in HeLa cells. Positive WB detected in human brain tissue, HeLa cells. Observed molecular weight by Western-blot: 60kd

Tested applications :
ELISA, WB, IHC, IP

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
Heat shOCk 70 kDa protein 13 antibody; HSPA13 antibody; STCH antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of HSPA13 recombinant protein (Accession Number: NM_006948). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:1000IHC: 1:20-1:200

Background :
HSPA13 (Heat shock 70 kDa protein 13), also known as STCH (the stress 70 protein chaperone), is a member of the Hsp70 family of ATPase “stress” or “heat shock” proteins. Human STCH encodes a 60 kDa protein that is highly enriched in the ER. Recently it has been reported that overexpression of the HSPA13 gene reduces prion disease incubation time in mice.

References :
Grizenkova J, Akhtar S, Hummerich H. Overexpression of the Hspa13 (Stch) gene reduces prion disease incubation time in mice. Proceedings of the National Academy of Sciences of the United States of America. 109(34):13722-7. 2012.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel