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Name :
HSPBP1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
HSPBP1 Rabbit Polyclonal antibody. Positive IHC detected in human colon cancer. Positive WB detected in mouse testis tissue, human brain tissue, human heart tissue, human testis tissue. Observed molecular weight by Western-blot: 40kd

Tested applications :
ELISA, WB, IHC

Species reactivity :
human, mouse; other species not tested.

Alternative names :
HSPBP1 antibody; HSPBP antibody; Hsp70 binding protein 2 antibody; Hsp70 binding protein 1 antibody; Hsp70 interacting protein 2 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of HSPBP1 recombinant protein (Accession Number: NM_012267). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200

Background :
Hsp70-interacting protein (HSPBP1)is a protein of approximately 40 kilodaltons detected in cell extracts. Its mRNA is present in all tissues analyzed but is most abundant in heart and skeletal muscle. HSPBP1 binds the ATPase domain of Hsp70 and inhibits approximately 90% of the Hsp40-activated Hsp70 ATPase activity by preventing ATP binding to Hsp70.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel