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Name :
HTR3A Polyclonal Antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
Polyclonal antibody to HTR3A

Tested applications :
WB, IHC

Species reactivity :
Human, Mouse, Rat

Alternative names :
HTR3A antibody; 5-HT-3 antibody; 5-HT3A antibody; 5-HT3R antibody; 5HT3R antibody; HTR3 antibody; 5-hydroxytryptamine receptor 3A antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-241 of human HTR3A (NP_000860.2).

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage instructions :
Store at -20℃. Avoid freeze / thaw cycles.

Applications :
WB 1:500 – 1:2000IHC 1:50 – 1:200

Background :
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel