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Name :
HuA/B/C/D antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
HuA/B/C/D Rabbit Polyclonal antibody. Positive IP detected in mouse brain tissue. Positive WB detected in human cerebellum tissue, mouse cerebellum tissue, PC-13 cells. Positive IHC detected in human breast cancer tissue. Observed molecular weight by Western-blot: 40 kDa

Tested applications :
ELISA, WB, IHC, IP

Species reactivity :
Human,Mouse,Rat,Zebrafish; other species not tested.

Alternative names :
ELAV like protein 4 antibody; ELAVL4 antibody; Hu antigen D antibody; Hu C/D antibody; HUD antibody; PNEM antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of HuA/B/C/D recombinant protein (Accession Number: NM_001144774). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:1000-1:10000IP: 1:200-1:1000IHC: 1:20-1:200

Background :
Embryonic lethal, abnormal vision, Drosophila-like 4 (ELAVL4) is a human homologue of the Drosophilia gene ELAV, which is implicated in neuronal differentiation and maintenance. The ELAVL proteins are mRNA binding proteins and all members of the family contain three RNA-recognition motifs [PMID:12402251]. ELAVL-proteins also interact with inflammation-associated factors. The protein may be implicated in neurodegeneration through these complex mechanisms [PMID:15827745].

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel