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Name :
Anti-BLBP/FABP7 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
Rabbit polyclonal to BLBP/FABP7

Tested applications :
ELISA, WB

Species reactivity :
Human BLBP / FABP7

Alternative names :
MRG antibody; Blbp antibody; BFABP antibody; B-FABP antibody; MRG antibody; BLBP antibody; FABPB antibody; B-FABP antibody; LTR2-FABP7 antibody; BFABP antibody; B-FABP antibody; B-FABP antibody; Blbp antibody; BLBP antibody; brain antibody; brain antibody; brain lipid binding protein antibody; brain lipid binding protein antibody; brain-type fatty acid-binding protein antibody; brain-type fatty acid-binding protein antibody; Fabp7 antibody; FABP7 antibody; FABPB antibody; fatty acid binding protein 7 antibody; fatty acid binding protein 7 antibody; fatty acid-binding protein antibody; fatty acid-binding protein antibody; mammary-derived growth inhibitor related antibody; mammary-derived growth inhibitor-related antibody; MRG antibody; MRG antibody; RP11-548E19.1 antibody

Immunogen :
Human BLBP/FABP7 recombinant protein

Isotype :
Rabbit IgG

Preparation :
Produced in rabbits immunized with purified, recombinant Human BLBP / FABP7 (rh BLBP / FABP7; O15540; Met1-Ala132). BLBP / FABP7 specific IgG was purified by Human BLBP / FABP7 affinity chromatography.

Clonality :
Polyclonal

Formulation :
0.2 μm filtered solution in PBS with 5% trehalose

Storage instructions :
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Applications :
WB: 10-20 μg/mlELISA: 0.1-0.2 μg/mLThis antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human BLBP / FABP7. The detection limit for Human BLBP / FABP7 is

Background :
BLBP, also known as FABP7, is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP7 binds DHA with the highest affinity among all of the FABPs. FABPs may play roles in fatty acid uptake, transport, and metabolism. BLBP is expressed, during development, in radial glia by the activation of notch receptors. It was shown that reelin induces FABP7 expression in neural progenitor cells via notch-1 activation. BLBP variation is linked to weak prepulse inhibition(PPI) in mice and deficit in PPI is an endophenotypic trait observed in schizophrenia patients and their relatives.

References :
Shi YE, et al. (1997) Antitumor activity of the novel human breast cancer growth inhibitor, mammary-derived growth inhibitor-related gene, MRG. Cancer Res. 57(15):3084-91. Young JK, et al. (1997) Immunoreactivity for brain-fatty acid binding protein in gomori-positive astrocytes. Glia. 16(3):218-26. Xu LZ, et al. (1996) Ligand specificity of brain lipid-binding protein. J Biol Chem. 271(40): 24711-9.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel