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Name :
humanin antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
humanin Rabbit Polyclonal antibody. Positive IHC detected in human small intestine tissue, human colon tissue, human heart tissue.

Tested applications :
ELISA, IHC

Species reactivity :
Human; other species not tested.

Alternative names :
humanin antibody; l rRNA antibody; MTRNR2 antibody; RNR2 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of Peptide (Accession Number: NC_012920). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: IHC: 1:20-1:200

Background :
Humanin, also named as MT-RNR2, is a mitochondrial peptide. It plays a role as a neuroprotective factor. It protects against death induced by multiple different familial Alzheimer disease genes and beta amyloid proteins in Alzheimer disease. Humanin reduces the aggregation and fibrillary formation by suppressing the effect of APP on mononuclear phagocytes and acts by competitively inhibiting the access of FPRL1 to APP.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel