Name :
HUWE1 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HUWE1 Rabbit Polyclonal antibody. Positive WB detected in HEK-293. Observed molecular weight by Western-blot: 482 kDa
Tested applications :
ELISA, WB
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
ARF binding protein 1 antibody; ARF BP1 antibody; HECTH9 antibody; HSPC272 antibody; HUWE1 antibody; Ib772 antibody; KIAA0312 antibody; KIAA1578 antibody; Large structure of UREB1 antibody; LASU1 antibody; Mcl 1 ubiquitin ligase E3 antibody; MULE antibody; URE B1 antibody; URE binding protein 1 antibody; UREB1 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of HUWE1 recombinant protein (Accession Number: BC002602). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: N/A
Background :
Huwe1 encodes a HECT domain ubiquitin ligase. HUWE1 is a large protein (500 kDa) that has attracted considerable interest because several and quite disparate substrates have been assigned to this E3. HUWE1 is essential for proliferation of a subset of tumor cells, and negative regulator of TP53 during the colorectal carcinoma progression through the ubiquitination pathway mediated by the HECT domain. It has a role in regulating Berg-mann glia differentiation and this ubiquitin ligase orchestrates the programming of the neural progenitors that give rise to neurons and glia in the cerebellum.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
Integrin beta 3 Antibody
Vibostolimab
ATF4 Antibody: ATF4 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 39 kDa, targeting to ATF4. It can be used for WB,IHC-P,ICC/IF,IP,FC assays with tag free, in the background of Human, Mouse, Rat.
