Name :
HYAL4 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HYAL4 Rabbit Polyclonal antibody. Positive IP detected in mouse testis tissue. Positive WB detected in mouse testis tissue, NIH/3T3 cells. Positive IHC detected in human testis tissue, human placenta tissue. Observed molecular weight by Western-blot: 65 kDa
Tested applications :
ELISA, IHC, WB, IP
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
Hyal 4 antibody; HYAL4 antibody; Hyaluronidase 4 antibody; hyaluronoglucosaminidase 4 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of HYAL4 recombinant protein (Accession Number: XM_017011911). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:1000IP: 1:200-1:1000IHC: 1:20-1:200
Background :
Hyaluronic acid (HA), a glycosaminoglycan that is ubiquitously present in the extracellular space of higher animals, maintains matrix structure and controls cellular functions such as proliferation, differentiation, and locomotion. Hyaluronidases, enzymes that catabolize HA, are involved in development and tumorigenesis. Hyaluronidase-4 (HYAL4), a member of the hyaluronidase family, is a chondroitin sulfate (CS)-specific endo-β-N-acetylgalactosaminidase. The expression of hHYAL4 mRNA is not ubiquitous but restricted to placenta, skeletal muscle, and testis (PMID: 23086929). This polyclonal antibody raised against 29-460aa of human HYAL4. The apparent molecular weight is larger than the calculated molecular weight of 54 kDa, which is likely due to posttranslational modification, presumably by glycosylation (PMID: 19889881).
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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