Name :
Icam1 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Icam1 Rabbit Polyclonal antibody. Positive IHC detected in mouse liver tissue. Positive WB detected in mouse brain tissue. Observed molecular weight by Western-blot: 85-95 kDa
Tested applications :
ELISA, WB, IHC
Species reactivity :
Mouse,Rat; other species not tested.
Alternative names :
CD54 antibody; ICAM 1 antibody; Icam1 antibody; Ly 47 antibody; MALA 2 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of Recombinant Protein (Accession Number: NM_010493). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:1000-1:10000IHC: 1:20-1:200
Background :
ICAM-1 (Intercellular Adhesion Molecule-1, CD54) is a glycosylated, transmembrane protein, a member of Ig super family. This protein involves in cell adhesion by interacting with a number of 2 integrin family members such as LFA-1 and Mac-1. Its expression is regulated by chemokines. This protein migrates approximately 115 kDa on SDS gels.
References :
Roland CL, Dineen SP, Toombs JE. Tumor-derived intercellular adhesion molecule-1 mediates tumor-associated leukocyte infiltration in orthotopic pancreatic xenografts. Experimental biology and medicine (Maywood, N.J.). 235(2):263-70. 2010. Suzuki AM, Yoshimura A, Ozaki Y, Kaneko T, Hara Y. Cyclosporin A and phenytoin modulate inflammatory responses. Journal of dental research. 88(12):1131-6. 2009. Arakawa Y, Shimada M, Utsunomiya T, Imura S, Morine Y, Ikemoto T. Effects of pegylated interferon α2b on metastasis of hepatocellular carcinoma. The Journal of surgical research. 172(1):95-101. 2012. Zhu H, Shao Q, Sun X. Bone marrow cells: Important role on neovascularization of hepatocellular carcinoma. Journal of gastroenterology and hepatology. 27(7):1241-51. 2012. Sun XT, Yuan XW, Zhu HT. Endothelial precursor cells promote angiogenesis in hepatocellular carcinoma. World journal of gastroenterology. 18(35):4925-33. 2012. Garin A, Meyer-Hermann M, Contie M. Toll-like receptor 4 signaling by follicular dendritic cells is pivotal for germinal center onset and affinity maturation. Immunity. 33(1):84-95. 2010. Chen G, Zhao J, Yin Y. C-type natriuretic peptide attenuates LPS-induced endothelial activation: involvement of p38, Akt, and NF-κB pathways. Amino acids. 46(12):2653-63. 2014. Wang YS, Li YX, Zhao P. Anti-inflammation Effects of Oxysophoridine on Cerebral Ischemia-Reperfusion Injury in Mice. Inflammation. 38(6):2259-68. 2015.
Related websites: https://www.medchemexpress.com/antibodies.html
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