Name :
ID2 Polyclonal Antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Polyclonal antibody to ID2
Tested applications :
WB, IHC
Species reactivity :
Human, Mouse, Rat
Alternative names :
ID2 antibody; GIG8 antibody; ID2A antibody; ID2H antibody; bHLHb26 antibody; DNA-binding protein inhibitor ID-2 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 75-134 of human ID2 (NP_002157.2).
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage instructions :
Store at -20℃. Avoid freeze / thaw cycles.
Applications :
WB 1:500 – 1:2000IHC 1:50 – 1:200
Background :
Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
Jagged1 Antibody
Nivolumab (anti-PD-1)
Gli1 Antibody: Gli1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 118 kDa, targeting to Gli1. It can be used for WB,IHC-P assays with tag free, in the background of Mouse, Rat.
