Name :
Iduronate 2 sulfatase antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Iduronate 2 sulfatase Mouse Monoclonal antibody. Positive WB detected in Human placenta, human brain tissue, human placenta tissue. Positive IHC detected in human liver tissue. Positive IF detected in HepG2 cells. Observed molecular weight by Western-blot: 76 kDa, 55 kDa
Tested applications :
ELISA, WB, IHC, IF
Species reactivity :
Human; other species not tested.
Alternative names :
IDS antibody; iduronate 2 sulfatase antibody; Idursulfase antibody
Immunogen :
Isotype :
Mouse IgG1
Preparation :
This antibody was obtained by immunization of Iduronate 2 sulfatase recombinant protein (Accession Number: BC006170). Purification method: Protein G purified.
Clonality :
Monoclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200IF: 1:20-1:200
Background :
Iduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome, an X chromosome-linked disease. An internal proteolytic cleavage occurs to produce the mature IDS present in human liver shown to contain a 42 kDa polypeptide N-terminal to a 14 kDa polypeptide.(PMID:2122463).
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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