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Name :
IFIT1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
IFIT1 Rabbit Polyclonal antibody. Positive IHC detected in human breast cancer, human liver cancer. Positive WB detected in U-937 cells, HeLa cells, LPS treated RAW 264.7 cells. Observed molecular weight by Western-blot: 55 Kda

Tested applications :
ELISA, IHC, WB

Species reactivity :
Human; other species not tested.

Alternative names :
G10P1 antibody; GARG 16 antibody; IFI 56 antibody; IFI 56K antibody; IFI56 antibody; IFIT 1 antibody; IFIT1 antibody; IFNAI1 antibody; ISG56 antibody; RNM561 antibody

Immunogen :
Human IFIT1 Recombinant protein (His tag)

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of IFIT1 recombinant protein (Accession Number: NM_001548). Purification method: Antigen Affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200

Background :
IFIT1 is, also known as glucocorticoid-attenuated response gene 16 protein (GARG-16), is a 463 amino acid protein belonging to the IFIT family. IFIT genes comprise a large family with three (Ifit1, Ifit2, and Ifit3) and four (IFIT1, IFIT2, IFIT3, and IFIT5) members in mice and humans, respectively. IFIT1 specifically bound virus PPP-RNA forms a complex with IFIT2 and IFIT3 to sequester the viral PPP-RNA and prevent virus replication.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel