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Name :
IFIT2 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
IFIT2 Rabbit Polyclonal antibody. Positive IHC detected in human skin cancer tissue, human kidney tissue. Positive IF detected in HepG2 cells. Positive IP detected in mouse skin tissue. Positive WB detected in A431 cells, RAW 264.7 cells. Observed molecular weight by Western-blot: 50-55 kDa

Tested applications :
ELISA, WB, IHC, IF, IP

Species reactivity :
Human, Mouse; other species not tested.

Alternative names :
cig42 antibody; G10P2 antibody; GARG 39 antibody; IFI 54 antibody; IFI 54K antibody; IFI54 antibody; IFIT 2 antibody; IFIT2 antibody; ISG 54 K antibody; ISG 54K antibody; ISG54 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of IFIT2 recombinant protein (Accession Number: BC032839). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:1000IP: 1:200-1:1000IHC: 1:20-1:200IF: 1:10-1:100

Background :
IFIT2 belongs to the IFIT family. It contains 6 TPR repeats. IFIT genes comprise a large family with three (Ifit1, Ifit2, and Ifit3) and four (IFIT1, IFIT2, IFIT3, and IFIT5) members in mice and humans, respectively. IFIT proteins are produced in human body that are supposed to confer immunity against viral infection. These proteins are generally produced during viral infection, Interferon (IFN) treatment, and during pathogen recognition (Pathogen associated molecular pattern recognition) by immune system during infections.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel