Name :
IFIT5 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
IFIT5 Rabbit Polyclonal antibody. Positive IP detected in A375 cells. Positive WB detected in A375 cells, PC-3 cells. Positive IHC detected in human skin cancer tissue. Observed molecular weight by Western-blot: 56-58 kDa,48 kDa
Tested applications :
ELISA, WB, IHC, IP
Species reactivity :
Human; other species not tested.
Alternative names :
FLJ53857 antibody; FLJ92678 antibody; IFIT 5 antibody; IFIT5 antibody; RI58 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of IFIT5 recombinant protein (Accession Number: NM_012420). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IP: 1:200-1:1000IHC: 1:20-1:200
Background :
IFIT5, also named as Interferon-induced 58 kDa protein or RI58, is a 482 amino acid protein, which contains eight TPR repeats and belongs to the IFIT family. IFIT5 localizes in the Cell projection. Interferon-induced RNA-binding protein that specifically binds single-stranded RNA bearing a 5′-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs.
References :
Zhang B, Liu X, Chen W, Chen L. IFIT5 potentiates anti-viral response through enhancing innate immune signaling pathways. Acta biochimica et biophysica Sinica. 45(10):867-74. 2013.
Related websites: https://www.medchemexpress.com/antibodies.html
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