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Name :
IGF2BP2 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
IGF2BP2 Rabbit Polyclonal antibody. Positive IHC detected in human pancreas cancer tissue. Positive IP detected in HEK-293 cells. Positive WB detected in human kidney tissue, COLO 320 cells, human heart tissue. Observed molecular weight by Western-blot: 65 kDa

Tested applications :
ELISA, WB, IHC, IP

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
IGF II mRNA binding protein 2 antibody; IGF2 mRNA binding protein 2 antibody; IGF2BP2 antibody; IMP 2 antibody; IMP2 antibody; p62 antibody; VICKZ family member 2 antibody; VICKZ2 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of IGF2BP2 recombinant protein (Accession Number: NM_006548). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:2000IHC: 1:20-1:200

Background :
Insulin-like growth factor 2 mRNA-binding protein 2(IGF2BP2), ia a member of a family of mRNA binding protein, which can bind to several mammalian cells’ mRNAs. Thus it may involve in the regulation of translation of mRNA. IGF2BP2’s polymorphisms is risk factor for developing type 2 diabetes. This antibody raise against part of N-terminus of human IGF2BP2.

References :
Li W, Liu D, Chang W. Role of IGF2BP3 in trophoblast cell invasion and migration. Cell death & disease. 5:e1025. 2014.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel