Name :
IGF2R-Specific antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
IGF2R-Specific Rabbit Polyclonal antibody. Positive FC detected in HepG2 cells. Positive IHC detected in human liver cancer tissue, human liver tissue. Positive IF detected in HepG2 cells. Positive IP detected in HepG2 cells. Positive WB detected in HepG2 cells, A431 cells, L02 cells. Observed molecular weight by Western-blot: 274 kDa
Tested applications :
ELISA, WB, IHC, IF, IP, FC
Species reactivity :
Human; other species not tested.
Alternative names :
CD222 antibody; CI Man 6 P receptor antibody; CI MPR antibody; CIMPR antibody; IGF II receptor antibody; IGF2R antibody; M6P R antibody; M6P/IGF2 receptor antibody; M6P/IGF2R antibody; M6PR antibody; MPR 300 antibody; MPR1 antibody; MPRI antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of Peptide (Accession Number: NM_000876). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:1000-1:10000IP: 1:200-1:2000IHC: 1:20-1:200IF: 1:20-1:200
Background :
IGF2R, also named as MPRI, CI Man-6-P receptor, CI-MPR, M6PR, IGF-II receptor, M6P/IGF2R, MPR 300 and CD222, belongs to the MRL1/IGF2R family. IGF2R transports of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. IGF2R is a lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. IGF2R acts as a positive regulator of T-cell coactivation, by binding DPP4. The antibody is specific to IGF2R.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
Phospho-PTEN (Ser380) Antibody
CEACAM6 Antibody (YA3351)
Bak Antibody (YA592): Bak Antibody (YA592) is a non-conjugated and Rabbit origined monoclonal antibody about 23 kDa, targeting to Bak. It can be used for WB,ICC/IF,IHC-P,IP,FC assays with tag free, in the background of Human, Mouse.
