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Name :
IGFBP4 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
IGFBP4 Rabbit Polyclonal antibody. Positive IF detected in C6 cells. Positive WB detected in C6 cells. Positive IP detected in C6 cells. Observed molecular weight by Western-blot: 40 kDa

Tested applications :
ELISA, WB, IF, IP

Species reactivity :
Human, Rat; other species not tested.

Alternative names :
BP 4 antibody; HT29 IGFBP antibody; IBP 4 antibody; IBP4 antibody; IGF binding protein 4 antibody; IGFBP 4 antibody; IGFBP4 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of IGFBP4 recombinant protein (Accession Number: NM_001552). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IP: 1:200-1:2000IF: 1:10-1:100

Background :
Insulin-like growth factor-binding protein 4 (IGFBP4), also named as IBP4, is a 258 amino acid porotein, which contains one IGFBP N-terminal domain and one thyroglobulin type-1 domain. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. IGFBP4 is a secreted protein and calculated molecular weight is 28 kDa. The modified IGFBP4 protein is about 40 kDa.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel