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Name :
IGFBP5 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
IGFBP5 Rabbit Polyclonal antibody. Positive WB detected in SKOV-3 cells. Positive IF detected in SKOV-3 cells. Observed molecular weight by Western-blot: 33 kDa

Tested applications :
ELISA, WB, IF

Species reactivity :
Human; other species not tested.

Alternative names :
IBP 5 antibody; IBP5 antibody; IGF binding protein 5 antibody; IGFBP 5 antibody; IGFBP5 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of Peptide (Accession Number: NM_000599). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IF: 1:20-1:200

Background :
IGFBP5, also named as IBP5, prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. It alter the interaction of IGFs with their cell surface receptors. This antibody is specific to IGFBL5.

References :
Lai G, Zhang Y, Wang L. Differences in IGF axis-related proteins in amniotic fluid of trisomy 21 and trisomy 18 using a multiple reaction monitoring approach. Prenatal diagnosis. 34(12):1146-52. 2014. Chen SX, Xu XE, Wang XQ. Identification of colonic fibroblast secretomes reveals secretory factors regulating colon cancer cell proliferation. Journal of proteomics. 110:155-71. 2014.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel