Name :
IL-10 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
IL-10 Mouse Monoclonal antibody. Positive IHC detected in human pancreas cancer tissue. Positive WB detected in ag14870, Transfected HEK-293 cells. Observed molecular weight by Western-blot: 22 kDa
Tested applications :
ELISA, WB, IHC
Species reactivity :
Human; other species not tested.
Alternative names :
CSIF antibody; IL 10 antibody; IL10 antibody; IL-10 antibody; IL10A antibody; interleukin 10 antibody; TGIF antibody
Immunogen :
Isotype :
Mouse IgG2b
Preparation :
This antibody was obtained by immunization of IL-10 recombinant protein (Accession Number: NM_000572). Purification method: Protein A purified.
Clonality :
Monoclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:2000-1:20000IHC: 1:50-1:500
Background :
Interleukin (IL)-10 is an anti-inflammatory cytokine, produced by T helper (Th) cells, macrophages, monocytes, and B cells, that plays a crucial role in preventing inflammatory and autoimmune pathologies. It downregulates the expression of Th1 cytokines, MHC class II antigens, and co-stimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-κB activity, and is involved in the regulation of the JAK-STAT signaling pathway. IL-10, along with its receptors, describes an important role in pathogenesis of various diseases, including infectious, inflammatory, autoimmune diseases. IL-10 mutations are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
RUNX2 Antibody
JNK Antibody
LC3B Antibody: LC3B Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 15 kDa, targeting to LC3B. It can be used for WB,ICC/IF,IHC-F,IHC-P assays with tag free, in the background of Human, Mouse, Rat.
