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Name :
IL-28A antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
IL-28A Mouse Monoclonal antibody. Positive WB detected in ag18525. Positive IHC detected in human tonsillitis tissue, human small intestine tissue. Observed molecular weight by Western-blot: 34 kDa

Tested applications :
ELISA, WB, IHC

Species reactivity :
Human; other species not tested.

Alternative names :
Cytokine Zcyto20 antibody; IFN lambda 2 antibody; IFNL2 antibody; IL 28A antibody; IL28A antibody; IL-28A antibody; Interferon lambda 2 antibody; Interleukin 28A antibody; ZCYTO20 antibody

Immunogen :
Human IL28A Recombinant protein (GST tag)

Isotype :
Mouse IgG1

Preparation :
This antibody was obtained by immunization of IL-28A recombinant protein (Accession Number: NM_172138). Purification method: Protein G purified.

Clonality :
Monoclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:5000-1:50000IHC: 1:20-1:200

Background :
IL28A, also named as IFNL2 and ZCYT020, is a cytokine with immunomodulatory activity. It up-regulates MHC class I antigen expression. IL28A is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1. The ligand/receptor complex seems to signal through the Jak-STAT pathway. It plays a significant role in the antiviral immune defense in the intestinal epithelium.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel