Name :
IL-4 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
IL-4 Mouse Monoclonal antibody. Positive IHC detected in human tonsillitis tissue. Positive WB detected in Jurkat cells, Transfected HEK-293 cells. Observed molecular weight by Western-blot: 18 kDa
Tested applications :
ELISA, WB, IHC
Species reactivity :
Human; other species not tested.
Alternative names :
B cell stimulatory factor 1 antibody; Binetrakin antibody; BSF 1 antibody; BSF1 antibody; IL 4 antibody; IL4 antibody; IL-4 antibody; interleukin 4 antibody; PS1TP5BP1 antibody
Immunogen :
Human IL4 Recombinant protein (His tag)
Isotype :
Mouse IgG2a
Preparation :
This antibody was obtained by immunization of IL-4 recombinant protein (Accession Number: NM_000589). Purification method: Protein G purified.
Clonality :
Monoclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200
Background :
IL4 is a cytokine produced by CD4+ T cells in response to helminthes and other extracellular parasites. It promotes the proliferation and differentiation of antigen presenting cells. IL4 also plays a pivotal role in antibody isotype switching and stimulates the production of IgE. This cytokine has been applied in the treatment of autoimmune disorder like multiple myeloma, cancer, psoriasis, and arthritis. IL4 has also been extensively applied to inhibit detrimental effect of Th1. It may promote the growth of epithelial tumors by mediating increased proliferation and survival.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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