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Name :
Il17a antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
Il17a Mouse Monoclonal antibody. Positive WB detected in Transfected HEK-293 cells.

Tested applications :
ELISA, WB

Species reactivity :
Human; other species not tested.

Alternative names :
Ctla 8 antibody; Ctla8 antibody; Il17 antibody; Il17a antibody; interleukin 17A antibody

Immunogen :

Isotype :
Mouse IgG2b

Preparation :
This antibody was obtained by immunization of Il17a recombinant protein (Accession Number: NM-010552). Purification method: Protein A purified.

Clonality :
Monoclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:1000-1:10000

Background :
Il17a is a pro-inflammatory cytokine as a member of the interleukin-17 family. It plays a central role in host defense against diverse pathogens. It is produced by activated T-cells and certain cell types of innate immune system. The active protein functions as either a homodimer with other interleukin-17 family members and signals through the interleukin-17 receptor to induce inflammatory cytokine production. Aberrant expression of this gene is associated with autoinflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel