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Name :
IL17RE antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
IL17RE Rabbit Polyclonal antibody. Positive IHC detected in human pancreas cancer tissue. Positive WB detected in human kidney tissue, PC-3 cells. Observed molecular weight by Western-blot: 75 kDa

Tested applications :
ELISA, WB, IHC

Species reactivity :
Human; other species not tested.

Alternative names :
FLJ23658 antibody; IL 17 receptor E antibody; IL 17RE antibody; IL17RE antibody; interleukin 17 receptor E antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of IL17RE recombinant protein (Accession Number: BC063110). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200

Background :
IL17RE, is a specific functional receptor for IL17C. It may be signaling through the NF-kappa-B and MAPK pathways. IL17Re may be a crucial regulator in innate immunity to bacterial pathogens. IL17RE has five isoforms with MW 31 kDa, 43 kDa, 58-62 kDa and 75 kDa.

References :
Pfeifer P, Voss M, Wonnenberg B. IL-17C is a mediator of respiratory epithelial innate immune response. American journal of respiratory cell and molecular biology. 48(4):415-21. 2013.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel