Name :
IL2 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
IL2 Mouse Monoclonal antibody. Positive WB detected in Jurkat cells. Positive IHC detected in human tonsillitis tissue, human breast cancer tissue. Observed molecular weight by Western-blot: 18 kDa
Tested applications :
ELISA, WB, IHC
Species reactivity :
Human; other species not tested.
Alternative names :
Aldesleukin antibody; IL 2 antibody; IL2 antibody; interleukin 2 antibody; lymphokine antibody; T cell growth factor antibody; TCGF antibody
Immunogen :
Human IL2 Recombinant protein (His tag)
Isotype :
Mouse IgG2a
Preparation :
This antibody was obtained by immunization of IL2 recombinant protein (Accession Number: NM_000586). Purification method: Protein A purified.
Clonality :
Monoclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200
Background :
IL2 is a secreted cytokine involved in the operation and regulation of immune system. IL2 plays a pivotal role in T-cell activation and effector functions, including T cell proliferation, interferon-γproduction and cytotoxicity. IL2 can stimulate the propagation of lymphocytes and induce the cytotoxic T lymphocytes and lymphokine-activated killer cells for tumor cells. IL2 also influences memory T cell homeostasis through the regulation of memory T cell numbers and enhances major histocompatibility complex II (MHC II) expression on tumor cells.
References :
Wang C, Chen K, Xia Y. N-acetylcysteine attenuates ischemia-reperfusion-induced apoptosis and autophagy in mouse liver via regulation of the ROS/JNK/Bcl-2 pathway. PloS one. 9(9):e108855. 2014.
Related websites: https://www.medchemexpress.com/antibodies.html
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