Name :
IL31RA Polyclonal Antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Polyclonal antibody to IL31RA
Tested applications :
WB
Species reactivity :
Human, Mouse
Alternative names :
IL31RA antibody; CRL antibody; CRL3 antibody; GLM-R antibody; GLMR antibody; GPL antibody; IL-31RA antibody; PLCA2 antibody; PRO21384 antibody; hGLM-R antibody; interleukin 31 receptor A antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human IL31RA (NP_001229568.1).
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage instructions :
Store at -20℃. Avoid freeze / thaw cycles.
Applications :
WB 1:500 – 1:2000
Background :
Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1 (By similarity). Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro (By similarity).
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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