Name :
IMPDH1 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
IMPDH1 Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, A431 cells, mouse spleen tissue. Positive IP detected in HeLa cells. Positive IHC detected in human ovary tumor tissue, human tonsillitis tissue. Positive IF detected in HeLa cells. Observed molecular weight by Western-blot: 53-60 kDa
Tested applications :
ELISA, WB, IHC, IP, IF
Species reactivity :
Human, Mouse, Rat; other species not tested.
Alternative names :
DKFZp781N0678 antibody; IMP dehydrogenase 1 antibody; IMPD antibody; IMPD 1 antibody; IMPD1 antibody; IMPDH 1 antibody; IMPDH I antibody; IMPDH1 antibody; LCA11 antibody; RP10 antibody; sWSS2608 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of IMPDH1 recombinant protein (Accession Number: NM_183243). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:1000-1:10000IP: 1:1000-1:10000IHC: 1:20-1:200IF: 1:20-1:200
Background :
IMPDH1(Inosine-5′-monophosphate dehydrogenase 1) is also named as IMPD1, IMP dehydrogenase 1 and belongs to the IMPDH/GMPR family. It catalyzes the rate limiting step of de novo guanine synthesis and an important target for the development of drugs with both chemotherapeutic and immunosuppressive activity. It may also have a role in the development of malignancy and the growth progression of some tumors. This protein has 7 isoforms produced by alternative splicing.
References :
Gunter JH, Thomas EC, Lengefeld N. Characterisation of inosine monophosphate dehydrogenase expression during retinal development: differences between variants and isoforms. The international journal of biochemistry & cell biology. 40(9):1716-28. 2008.
Related websites: https://www.medchemexpress.com/antibodies.html
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