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Name :
INF2 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
INF2 Rabbit Polyclonal antibody. Positive WB detected in A431 cells, HeLa cells, mouse brain tissue, NIH/3T3 cells. Positive IP detected in NIH/3T3 cells. Positive IHC detected in human kidney tissue. Positive IF detected in NIH/3T3 cells. Observed molecular weight by Western-blot: 180-200 kDa

Tested applications :
ELISA, WB, IHC, IF, IP

Species reactivity :
Human, Mouse; other species not tested.

Alternative names :
C14orf151 antibody; C14orf173 antibody; DKFZp762A0214 antibody; FLJ22056 antibody; HBEBP2 binding protein C antibody; INF2 antibody; Inverted formin 2 antibody; pp9484 antibody

Immunogen :
Human INF2 Recombinant protein (GST tag)

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of INF2 recombinant protein (Accession Number: BC008756). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:1000-1:10000IP: 1:200-1:2000IHC: 1:20-1:200IF: 1:20-1:200

Background :
INF2 represents inverted formin, FH2 and WH2 domain containing

References :
Shao X, Li Q, Mogilner A, Bershadsky AD, Shivashankar GV. Mechanical stimulation induces formin-dependent assembly of a perinuclear actin rim. Proceedings of the National Academy of Sciences of the United States of America. 112(20):E2595-601. 2015. Tamura H, Nakazato H, Kuraoka S, Yoneda K, Takahashi W, Endo F. Reduced INF2 expression in nephrotic syndrome is possibly related to clinical severity of steroid resistance in children. Nephrology (Carlton, Vic.). 2015. Skau CT, Plotnikov SV, Doyle AD, Waterman CM. Inverted formin 2 in focal adhesions promotes dorsal stress fiber and fibrillar adhesion formation to drive extracellular matrix assembly. Proceedings of the National Academy of Sciences of the United States of America. 112(19):E2447-56. 2015.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel