Name :
INPP5B antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
INPP5B Rabbit Polyclonal antibody. Positive WB detected in mouse spleen tissue, HeLa cells, human placenta tissue. Positive IHC detected in human lymphoma tissue. Observed molecular weight by Western-blot: 75 kDa
Tested applications :
ELISA, WB, IHC
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
5PTase antibody; INPP5B antibody; Phosphoinositide 5 phosphatase antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of INPP5B recombinant protein (Accession Number: BC058932). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200
Background :
INPP5B(Type II inositol 1,4,5-trisphosphate 5-phosphatase) is also named as ocRL2,5PTase, 75 kDa inositol polyphosphate-5-phosphatase and belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family. This protein, originally described in platelets, is one of at least three known enzymes capable of dephosphorylating inositol-1,4,5-trisphosphate (IP3) to inositol-1,4-bisphosphate (IP2)(PMID:8125013). It has 4 isoforms produced by alternative splicing.
References :
Luo N, Kumar A, Conwell M, Weinreb RN, Anderson R, Sun Y. Compensatory Role of Inositol 5-Phosphatase INPP5B to OCRL in Primary Cilia Formation in Oculocerebrorenal Syndrome of Lowe. PloS one. 8(6):e66727. 2013.
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
HDAC2 Antibody
Ras Antibody
RBM3 Antibody: RBM3 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 17 kDa, targeting to RBM3. It can be used for ICC,IHC-P,FC assays with tag free, in the background of Mouse, Human, Rat.
