Name :
Insulin antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Insulin Mouse Monoclonal antibody. Positive IHC detected in human pancreas tissue, mouse pancreas tissue.
Tested applications :
ELISA, IHC
Species reactivity :
Human, Mouse; other species not tested.
Alternative names :
ILPR antibody; INS antibody; Insulin antibody; IRDN antibody
Immunogen :
Isotype :
Mouse IgG2a
Preparation :
This antibody was obtained by immunization of Insulin recombinant protein (Accession Number: NM_001185097). Purification method: Protein A purified.
Clonality :
Monoclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: IHC: 1:500-1:5000
Background :
Insulin is a peptide hormone, produced by beta cells of the pancreas, and is central to regulating carbohydrate and fat metabolism in the body. It participates in glucose utilization, protein synthesis and in the formation and storage of neutral lipids. Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Defects in insulin results in type 1 diabetes mellitus. Insulin may also exist 36 kDa form corresponding to the hexameric insulin form.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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