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Name :
Anti-BPIFB1 / LPLUNC1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
Rabbit polyclonal to BPIFB1 / LPLUNC1

Tested applications :
ELISA, IHC-P

Species reactivity :
Human BPIFB1 / LPLUNC1

Alternative names :
BPI fold containing family B antibody; member 1 antibody; Bpifb1 antibody; RP23-154J12.1 antibody; Lplunc1 antibody; BPI fold-containing family B member 1 antibody; long palate antibody; lung and nasal epithelium carcinoma associated 1 antibody; long palate antibody; lung and nasal epithelium carcinoma-associated protein 1 antibody; von Ebner minor salivary gland protein antibody; von Ebner minor salivary protein antibody; LPLUNC1 antibody; C20orf114 antibody; Lplunc1 antibody

Immunogen :
Human BPIFB1 / LPLUNC1 (His Tag) recombinant protein

Isotype :
Rabbit IgG

Preparation :
Produced in rabbits immunized with purified, recombinant Human BPIFB1 / LPLUNC1 (rh BPIFB1 / LPLUNC1; AAH08429.1; Met1-Gln484). BPIFB1 / LPLUNC1 specific IgG was purified by Human BPIFB1 / LPLUNC1 affinity chromatography.

Clonality :
Polyclonal

Formulation :
0.2 μm filtered solution in PBS

Storage instructions :
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Applications :
ELISA:0.1-0.2 μg/mLThis antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human BPIFB1 / LPLUNC1. The detection limit for Human BPIFB1 / LPLUNC1 is IHC-P: 0.1-1 μg/ml

Background :
BPIFB1, also known as LPLUNC1, belongs to the BPI/LBP/Plunc superfamily, plunc family. BPIFB1 may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. BPIFB1 is expressed in the upper respiratory tract and oral cavity, which may function in host defence. The expression of BPIF proteins is associated with CF lung disease in humans and mice. It is unclear if this elevation of protein production, which results from phenotypic alteration of the cells within the diseased epithelium, plays a role in the pathogenesis of the disease. BPIFB1 is an abundant, secreted product of goblet cells and minor mucosal glands of the respiratory tract and oral cavity and suggest that the protein functions in the complex milieu that protects the mucosal surfaces in these locations.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel