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Name :
Integrin alpha-5 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
Integrin alpha-5 Rabbit Polyclonal antibody. Positive WB detected in 3T3-L1 cells, A549 cells, COS-7 cells, HeLa cells, human placenta tissue. Observed molecular weight by Western-blot: 120-135 kDa

Tested applications :
ELISA, WB

Species reactivity :
Human, Mouse, Monkey; other species not tested.

Alternative names :
CD49e antibody; FNRA antibody; Integrin alpha 5 antibody; Integrin alpha F antibody; ITGA5 antibody; VLA 5 antibody; VLA5A antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of Integrin alpha-5 recombinant protein (Accession Number: NM_002205). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000

Background :
ITGA5 represents integrin, alpha 5 (fibronectin receptor, alpha polypeptide)

References :
Liu D, Zhang XX, Wan DY. Sine oculis homeobox homolog 1 promotes α5β1-mediated invasive migration and metastasis of cervical cancer cells. Biochemical and biophysical research communications. 446(2):549-54. 2014. Haraguchi M, Sato M, Ozawa M. CRISPR/Cas9n-Mediated Deletion of the Snail 1Gene (SNAI1) Reveals Its Role in Regulating Cell Morphology, Cell-Cell Interactions, and Gene Expression in Ovarian Cancer (RMG-1) Cells. PloS one. 10(7):e0132260. 2015.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel