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Name :
Interferon alpha antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
Interferon alpha Mouse Monoclonal antibody. Positive WB detected in Recombinant protein. Observed molecular weight by Western-blot: 22 kDa

Tested applications :
ELISA, WB

Species reactivity :
Human; other species not tested.

Alternative names :
IFL antibody; IFN antibody; IFN ALPHA antibody; IFN alpha 1/13 antibody; IFNA@ antibody; IFNA1 antibody; IFNA13 antibody; Interferon alpha 1/13 antibody; Interferon alpha D antibody; interferon antibody; alpha 1 antibody; Interferon-α1 antibody; LeIF D antibody

Immunogen :

Isotype :
Mouse IgG2a

Preparation :
This antibody was obtained by immunization of Interferon alpha recombinant protein (Accession Number: NM_024013). Purification method: Protein A purified.

Clonality :
Monoclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:5000-1:50000

Background :
IFNA1 (interferon-alpha) is a member of the Type I IFN (1) family best known for their antiviral activity. It is a key cytokine regulating the activity of B cells, T-helper cells (Th cells), cDCs and natural killer cells (NK cells). Interferon-alpha induces B cell maturation into plasma cells and immunoglobulin production. Interferon-alpha plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). Interferon-alpha was the first cytokine to show clinical benefit in the treatment of certain types of cancer, including melanoma, chronic myelogenous leukemia, and renal cancer.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel